An integrated ion-exchange membrane-based microfluidic device for irreversible dissociation and quantification of miRNA from ribonucleoproteins-Reference-Cited by-同舟云学术

An integrated ion-exchange membrane-based microfluidic device for irreversible dissociation and quantification of miRNA from ribonucleoproteins

Published:2023 Issue:2 Volume:23 Page:285-294
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

McCarthy Kyle P.¹^ORCID,Go David B.¹²^ORCID,Senapati Satyajyoti¹^ORCID,Chang Hsueh-Chia¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA

2. Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA

Abstract

An integrated ion-exchange membrane (IEM) based device for rapid and irreversible dissociation of protein-RNA complex (ribonucleoprotein, RNP) and quantification of its associated RNA.

Funder

NIH Office of the Director

National Heart, Lung, and Blood Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D2LC00517D

Reference53 articles.

1. RNA–protein interactions in human health and disease

2. The expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactions

3. Why do miRNAs live in the miRNP?

4. RNA structure drives interaction with proteins

5. Purification of cross-linked RNA-protein complexes by phenol-toluol extraction

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