Label-free purification and characterization of optogenetically engineered cells using optically-induced dielectrophoresis

Author:

Yang Jia123ORCID,Gu Yanyu124,Zhang Chuang12,Zhang Yuzhao123,Liang Wenfeng5ORCID,Hao Lina4,Zhao Ying6,Liu Lianqing12ORCID,Wang Wenxue12

Affiliation:

1. State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China

2. Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110169, China

3. University of Chinese Academy of Sciences, Beijing 100049, China

4. School of Mechanical Engineering and Automation, Northeastern University, Shenyang 110819, China

5. School of Mechanical Engineering, Shenyang Jianzhu University, Shenyang 110168, China

6. Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, China

Abstract

We propose label-free and nondestructive on-chip purification and characterization of optogenetically engineered cells, thus significantly enhancing their application performance.

Funder

National Key Research and Development Program of China

Liaoning Revitalization Talents Program

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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