Main interactions of dopamine and risperidone with the dopamine D2 receptor

Author:

Martínez Ana123ORCID,García-Gutiérrez Ponciano4563,Zubillaga Rafael A.4563,Garza Jorge4563,Vargas Rubicelia4563ORCID

Affiliation:

1. Instituto de Investigaciones en Materiales

2. Universidad Nacional Autónoma de México

3. Mexico

4. Departamento de Química

5. División de Ciencias Básicas e Ingeniería

6. Universidad Autónoma Metropolitana-Iztapalapa

Abstract

A comparison between dopamine and risperidone shows that weak non-covalent interactions are relevant in understanding the antipsychotic drug mechanism.

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Reference64 articles.

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3. D. W. Volk and D. A.Lewis , Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease , Academic Press , San Diego , 5th edn, 2015 , pp. 1293–1299

4. G. T. Konopaske and J. T.Coyle , Neurobiology of Brain Disorders , Academic Press , San Diego , 2015 , pp. 639–654

5. F. Fröhlich , Network neuroscience , Academic Press , New York , 2016 , pp. 309–318

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