Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering-Reference-Cited by-同舟云学术

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Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering

Published:2016 Issue:1 Volume:14 Page:335-344
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Guzzi C.¹²³⁴⁵,Alfarano P.⁶⁷⁸,Sutkeviciute I.⁹¹⁰¹¹¹²¹³,Sattin S.¹⁴¹⁵¹⁶¹⁷,Ribeiro-Viana R.¹²³,Fieschi F.⁹¹⁰¹¹¹²¹³,Bernardi A.¹⁴¹⁵¹⁶¹⁷,Weiser J.⁶⁷⁸,Rojo J.¹²³,Angulo J.¹²³¹⁸¹⁹,Nieto P. M.¹²³

Affiliation:

1. Glycosystems Laboratory. Instituto de Investigaciones Químicas (IIQ)/cicCartuja. CSIC/US

2. 41092 Sevilla

3. Spain

4. Dept. of Biotechnology and Biosciences University of Millano-Bicocca Piazza della Scienza 2 20126

5. Milan

6. Anterio Consult & Research GmbH

7. Augustaanlage 23 68165 Mannheim

8. Germany

9. Univ. Grenoble Alpes

10. Institut de Biologie Structurale (IBS)

11. F-38044 Grenoble

12. France

13. CNRS

14. Dipartimento di Chimica

15. Universita’ degli Studi di Milano

16. 20133 Milano

17. Italy

18. School of Pharmacy

19. University of East Anglia

Abstract

Multiple binding modes at the same binding site can explain the higher binding affinity of a pseudotrimannotrioside compared to a pseudomannobioside.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02025E

Reference60 articles.

1. Animal lectins: a historical introduction and overview

2. Chemical Biology of the Sugar Code

3. Roles of galectins in infection

4. Dendritic cells and the control of immunity

5. DC-SIGN: escape mechanism for pathogens

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