Polyhydroxylated GdDTPA-derivatives as high relaxivity magnetic resonance imaging contrast agents-Reference-Cited by-同舟云学术

Polyhydroxylated GdDTPA-derivatives as high relaxivity magnetic resonance imaging contrast agents

Published:2015 Issue:91 Volume:5 Page:74734-74743
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tei Lorenzo¹²³⁴,Barge Alessandro⁵⁶⁷⁴,Galli Matteo⁸⁹¹⁰⁴,Pinalli Roberta⁸⁹¹⁰⁴,Lattuada Luciano⁸⁹¹⁰⁴,Gianolio Eliana¹¹¹²⁶¹³⁴,Aime Silvio¹¹¹²⁶¹³⁴

Affiliation:

1. Dipartimento di Scienze e Innovazione Tecnologica

2. Università del Piemonte Orientale “Amedeo Avogadro”

3. 15121 Alessandria

4. Italy

5. Dipartimento di Scienza e Tecnologia del Farmaco

6. Università di Torino

7. 10125 Torino

8. Bracco Imaging SpA

9. Bracco Research Centre

10. 10010 Colleretto Giacosa

11. Department of Molecular Biotechnology and Health Sciences

12. Molecular Imaging Center

13. Torino

Abstract

Novel GdDTPA-like complexes bearing differently branched, highly hydrophilic, gluconyl moieties were synthesized to obtain high relaxivity agents (∼20 mM⁻¹ s⁻¹ at 25 °C) over a wide range of imaging fields (0.5–3 T).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA15071J

Reference48 articles.

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