Partial fusion of a cytochrome P450 system by carboxy-terminal attachment of putidaredoxin reductase to P450cam (CYP101A1)
Author:
Affiliation:
1. Department of Chemistry
2. University of Oxford
3. Inorganic Chemistry Laboratory
4. Oxford OX1 3QR
5. UK
Abstract
Fusion of two non-interacting components of a class I Cytochrome P450 system more than doubles the rate of camphor hydroxylation.
Funder
Biotechnology and Biological Sciences Research Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2016/CY/C6CY01042C
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1. Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone
2. Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism
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