Debugging: putting the synthetic yeast chromosome to work
Author:
Affiliation:
1. Frontiers Science Center for Synthetic Biology
2. Key Laboratory of Systems Bioengineering (Ministry of Education)
3. School of Chemical Engineering and Technology
4. Tianjin University
5. Tianjin
Abstract
This review summarizes strategies used to map and repair various bugs in synthetic genomic sequences and provides guidance for the construction of synthetic yeast chromosomes that are capable of maintaining cell fitness.
Funder
National Key Research and Development Program of China
National Natural Science Foundation of China
Natural Science Foundation of Tianjin
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/SC/D0SC06924H
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