Transition-metal-free oxidative carboazidation of acrylamides via cascade C–N and C–C bond-forming reactions

Author:

Qiu Jun12345,Zhang Ronghua12345

Affiliation:

1. Department of Chemistry

2. Tongji University

3. Shanghai 200092, P. R. China

4. Key Laboratory of Yangtze River Water Environment

5. Ministry of Education

Abstract

A novel transition-metal-free oxidative carboazidation of acrylamides using inexpensive NaN3 and K2S2O8 was achieved, which not only provided an efficient method to prepare various N3-substituted oxindoles, but also represented a novel strategy for C–N and C–C bond formation via a free-radical cascade process.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference126 articles.

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3. S. Bräse and K.Banert , in Organic Azides , Wiley-VCH , Weinheim , 2010

4. Vinyl and Alkynyl Azides: Well-Known Intermediates in the Focus of Modern Synthetic Methods

5. AIDS-driven nucleoside chemistry.

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