AIE/FRET-based versatile PEG-Pep-TPE/DOX nanoparticles for cancer therapy and real-time drug release monitoring

Author:

Wang Tian-Tian12345ORCID,Wei Qi-Chun67839,Zhang Zhen-Tao12345,Lin Meng-Ting12345,Chen Jie-Jian12345,Zhou Yi12345,Guo Ning-Ning12345,Zhong Xin-Cheng12345,Xu Wen-Hong67839,Liu Zhan-Xiang103115,Han Min12345ORCID,Gao Jian-Qing12345ORCID

Affiliation:

1. Institute of Pharmaceutics

2. College of Pharmaceutical Sciences

3. Zhejiang University

4. Hangzhou

5. China

6. Department of Radiation Oncology

7. Key Laboratory of Cancer Prevention and Intervention

8. the Second Affiliated Hospital

9. College of Medicine

10. Department of Chemistry

11. Hangzhou, 310058

Abstract

Based on the biological significance of self-assembling peptides in program cell death, promoting proliferation of stem cells and suppressing immune responses, stimuli-responsive polypeptide nanoparticles have attracted more and more attention.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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