A novel ionic liquid-based monolithic column and its application in the efficient separation of proteins and small molecules by high-performance liquid chromatography-Reference-Cited by-同舟云学术

A novel ionic liquid-based monolithic column and its application in the efficient separation of proteins and small molecules by high-performance liquid chromatography

Published:2015 Issue:1 Volume:7 Page:218-225
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Qin Junxiao¹²³⁴²,Bai Ligai¹²³⁴²,Wang Jiafei¹²³⁴²,Ma Yamin¹²³⁴²,Liu Haiyan¹²³⁴²,He Shuai³⁴²,Li Tengteng³⁴²,An Ying³⁴²

Affiliation:

1. Key Laboratory of Pharmaceutical Quality Control of Hebei Province

2. China

3. College of Pharmaceutical Sciences

4. Hebei University

Abstract

Ionic liquid was used to prepare a monolith. The resulting porous monolith had a high specific surface area and was used as the stationary phase for HPLC, showing excellent performance to separate small molecules and protein.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AY/C4AY01812E

Reference19 articles.

1. Monolithic columns in high-performance liquid chromatography

2. Recent advances in preparation and application of hybrid organic-silica monolithic capillary columns

3. Polymeric ionic liquid modified organic-silica hybrid monolithic column for capillary electrochromatography

4. Poly(N-isopropylacrylamide-co-N,N′-methylene bisacrylamide) monolithic column embedded with γ-alumina nanoparticles microextraction coupled with high-performance liquid chromatography for the determination of synthetic food dyes in soft drink samples

5. Preparation and application of novel zwitterionic monolithic column for hydrophilic interaction chromatography

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