Base-catalyzed cascade synthesis of 2,3-dihydrofuro[2,3-b]pyridines and 2,3-dihydro-1H-pyrrolo[2,3-b]pyridines from N-propargylic β-enaminones-Reference-Cited by-同舟云学术

Base-catalyzed cascade synthesis of 2,3-dihydrofuro[2,3-b]pyridines and 2,3-dihydro-1H-pyrrolo[2,3-b]pyridines from N-propargylic β-enaminones

Published:2017 Issue:54 Volume:53 Page:7497-7500
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Yang Xiaobing¹²³⁴⁵,Hu Fangzhong¹²³⁴^ORCID,Wang Yang¹²³⁴,Yang Chiming¹²³⁴⁵,Zou Xiaomao¹²³⁴,Liu Jiahui¹²³⁴,Zhang Qichun⁶⁷⁸⁹¹⁰

Affiliation:

1. State Key Laboratory and Institute of Elemento-Organic Chemistry

2. Nankai University

3. Tianjin 300071

4. China

5. Department of Chemistry

6. School of Materials Science Engineering

7. Nanyang Technological University

8. Singapore

9. Division of Chemistry and Biological Chemistry

10. School of Physical and Mathematical Sciences

Abstract

A novel protocol to prepare dihydrofuropyridine and dihydropyrrolopyridine derivatives from KOH-catalyzed reactions between N-propargylic β-enaminones and arylaldehydes or N-sulfonyl imines has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC03308G

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3. Analysis of the reactions used for the preparation of drug candidate molecules

4. Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model

5. IBX mediated reaction of β-enamino esters with allylic alcohols: a one pot metal free domino approach to functionalized pyridines

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