Amidation of methyl ester-functionalised poly(2-oxazoline)s as a powerful tool to create dual pH- and temperature-responsive polymers as potential drug delivery systems-Reference-Cited by-同舟云学术

Amidation of methyl ester-functionalised poly(2-oxazoline)s as a powerful tool to create dual pH- and temperature-responsive polymers as potential drug delivery systems

Published:2023 Issue:17 Volume:14 Page:2034-2044
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Leiske Meike N.¹^ORCID,Singha Ronak¹,Jana Somdeb¹,De Geest Bruno G.²^ORCID,Hoogenboom Richard¹^ORCID

Affiliation:

1. Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, B-9000 Ghent, Belgium

2. Department of Pharmaceutics and Cancer Research Institute Ghent (CRIG), Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium

Abstract

We present the synthesis of different amine-functionalised poly(2-oxazoline)s, their dual pH and temperature response as well as their capability to as promising stimuli responsive drug delivery vectors.

Funder

Fonds Wetenschappelijk Onderzoek

Bijzonder Onderzoeksfonds UGent

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/PY/D3PY00050H

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1. Polymer therapeutics-prospects for 21st century: The end of the beginning

2. Nanomedicine(s) under the Microscope