SypHer3s: a genetically encoded fluorescent ratiometric probe with enhanced brightness and an improved dynamic range-Reference-Cited by-同舟云学术

SypHer3s: a genetically encoded fluorescent ratiometric probe with enhanced brightness and an improved dynamic range

Published:2018 Issue:23 Volume:54 Page:2898-2901
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Ermakova Y. G.¹²³⁴²,Pak V. V.¹²³,Bogdanova Y. A.¹²³,Kotlobay A. A.¹²³,Yampolsky I. V.¹²³,Shokhina A. G.¹²³,Panova A. S.¹²³⁵⁶,Marygin R. A.¹²³^ORCID,Staroverov D. B.¹²³,Bilan D. S.¹²³⁴²,Sies H.⁷⁸⁹¹⁰¹¹,Belousov V. V.¹²³⁴²^ORCID

Affiliation:

1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences

2. Moscow

3. Russia

4. Pirogov Russian National Research Medical University

5. Department of Biochemistry

6. Biological Faculty

7. Institute of Biochemistry and Molecular Biology I

8. Heinrich-Heine-University Düsseldorf

9. Düsseldorf

10. Germany

11. Leibniz Institute for Environmental Medicine

Abstract

We designed a genetically encoded ratiometric fluorescent probe, SypHer3s, with enhanced brightness and optimized pK_a, which responds to pH changes in different cellular compartments.

Funder

Deutsche Forschungsgemeinschaft

Russian Foundation for Basic Research

National Foundation for Cancer Research

Deutscher Akademischer Austauschdienst

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C7CC08740C

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