Synthesis of novel symmetrical 2-oxo-spiro[indole-3,4′-pyridines] by a reaction of oxindoles with 1,2-diaza-1,3-dienes
Author:
Affiliation:
1. Department of Biomolecular Sciences
2. Section of Organic Chemistry and Organic Natural Compounds
3. University of Urbino “Carlo Bo”
4. 61029 Urbino (PU)
5. Italy
Abstract
Synthesis of symmetrical 2-oxo-spiro[indole-3,4′-pyridines]: a novel example of spirocyclic oxindoles bearing a quaternary centre at the 3-position.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB01959H
Reference37 articles.
1. A. U. Rahman and A.Basha, Indole Alkaloids, Harwood Academic publishers, Amsterdam, 1997
2. Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids
3. Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents
4. Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies
5. Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors
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