Ginseng-derived exosome-like nanovesicles extracted by sucrose gradient ultracentrifugation to inhibit osteoclast differentiation-Reference-Cited by-同舟云学术

Ginseng-derived exosome-like nanovesicles extracted by sucrose gradient ultracentrifugation to inhibit osteoclast differentiation

Published:2023 Issue:12 Volume:15 Page:5798-5808
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Seo Kwansung¹^ORCID,Yoo Ji Hye²^ORCID,Kim Jisu³^ORCID,Min Sung Jun¹^ORCID,Heo Dong Nyoung⁴^ORCID,Kwon Il Keun⁴^ORCID,Moon Ho-Jin⁴^ORCID

Affiliation:

1. Department of Dentistry, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea

2. Department of Biomedical Science and Technology, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea

3. Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China

4. Department of Dental Materials, School of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea

Abstract

Ginseng-derived extracellular nanovesicles effectively blocked bone loss bothin vitroandin vivoby inhibiting osteoclast differentiation through RANKL-induced IκBα, JNK, and ERK activation.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR07018A

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