Metal-based anticancer agents as immunogenic cell death inducers: the past, present, and future

Author:

Sen Sajal1ORCID,Won Miae2ORCID,Levine Matthew S.1,Noh Yuvin2,Sedgwick Adam C.1ORCID,Kim Jong Seung2ORCID,Sessler Jonathan L.1ORCID,Arambula Jonathan F.13ORCID

Affiliation:

1. Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712-1224, USA

2. Department of Chemistry, Korea University, Seoul 02841, Korea

3. OncoTEX, Inc. 3800 North Lamar Blvd., Austin, Texas 78756, USA

Abstract

Immunogenic cell death (ICD) is a unique mode of cell death that could trigger tumour-specific immune response. Metal-based drugs which have emerged as promising agents within the lexicon of possible ICD inducers will be the topic of this review.

Funder

National Research Foundation of Korea

National Cancer Institute

Welch Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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