A novel withanolide with an unprecedented carbon skeleton from Physalis angulata

Author:

Sun Cheng-Peng12345,Kutateladze Andrei G.6789,Zhao Feng1011121314,Chen Li-Xia515161217,Qiu Feng12345ORCID

Affiliation:

1. Tianjin State Key Laboratory of Modern Chinese Medicine and School of Chinese Materia Medica

2. Tianjin University of Traditional Chinese Medicine

3. Tianjin 300193

4. China

5. Department of Natural Products Chemistry

6. Department of Chemistry and Biochemistry

7. University of Denver

8. Denver

9. USA

10. School of Pharmacy

11. Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)

12. Ministry of Education

13. Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong

14. Yantai University

15. School of Traditional Chinese Materia Medica

16. Key Laboratory of Structure-Based Drug Design & Discovery

17. Shenyang Pharmaceutical University

Abstract

Aromaphysalin A (1), possessing an exceptional C(11)–C(15) bond and a rearranged 4,9-cyclized aromatic ring, is isolated from of Physalis angulata.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference34 articles.

1. Natural withanolides: an overview

2. Antileishmanial Physalins fromPhysalis minima

3. A. S. Veleiro , J. C.Oberti and G.Burton, Studies in natural products chemistry, bioactive natural products, 2005, vol. 32, pp. 1019–1052

4. A. S. R. Anjaneyulu , D. S.Rao and P. W.Lequesne, Studies in natural products chemistry, bioactive natural products, 1998, vol. 20, pp. 135–261

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