Quantitative electrostatic force tomography for virus capsids in interaction with an approaching nanoscale probe-Reference-Cited by-同舟云学术

Quantitative electrostatic force tomography for virus capsids in interaction with an approaching nanoscale probe

Published:2022 Issue:34 Volume:14 Page:12232-12237
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Cooper Christopher D.¹²^ORCID,Addison-Smith Ian¹,Guzman Horacio V.³⁴^ORCID

Affiliation:

1. Department of Mechanical Engineering, Universidad Técnica Federico Santa María, 2390123 Valparaíso, Chile

2. Centro Científico Tecnológico de Valparaíso (CCTVal), 2390123 Valparaíso, Chile

3. Department of Theoretical Physics, Jožef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia

4. Departamento de Física Teórica de la Materia Condensada, Universidad Autónoma de Madrid, E-28049 Madrid, Spain

Abstract

Electrostatic interactions are crucial for the assembly and stability of virus capsids. Here we show with a high-res model the charge, dielectric and salt contributions of specific amino acids to the interaction force between a nanoprobe and viruses.

Funder

Universidad Técnica Federico Santa María

Fondo Nacional de Desarrollo Científico y Tecnológico

Javna Agencija za Raziskovalno Dejavnost RS

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR02526D

Reference44 articles.

1. Mapping Local Electrostatic Forces with the Atomic Force Microscope