A molecular view of cisplatin's mode of action: interplay with DNA bases and acquired resistance-Reference-Cited by-同舟云学术

A molecular view of cisplatin's mode of action: interplay with DNA bases and acquired resistance

Published:2015 Issue:7 Volume:17 Page:5155-5171
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Marques M. Paula M.¹²³⁴⁵,Gianolio Diego⁶⁷⁸,Cibin Giannantonio⁶⁷⁸,Tomkinson John⁹¹⁰¹¹⁸,Parker Stewart F.⁹¹⁰¹¹⁸,Valero Rosendo¹²³⁴⁵,Pedro Lopes R.¹²³⁴⁵,Batista de Carvalho Luis A. E.¹²³⁴⁵^ORCID

Affiliation:

1. Molecular Physical Chemistry R&D Unit

2. Fac. Science and Technology

3. Univ. Coimbra

4. 3004-535 Coimbra

5. Portugal

6. Diamond Light Source

7. STFC Harwell Science and Innovation Campus

8. UK

9. ISIS Facility

10. STFC Rutherford Appleton Laboratory

11. Didcot

Abstract

A definite molecular picture of cisplatin's MOA is presented, including a detailed interpretation of the glutathione-mediated drug scavenging process.

Funder

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CP/C4CP05183A

Reference72 articles.

1. Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

2. Platinum Compounds: a New Class of Potent Antitumour Agents

3. The resurgence of platinum-based cancer chemotherapy