Paramagnetic ultrasmall Ho2O3 and Tm2O3 nanoparticles: characterization of r2 values and in vivo T2 MR images at a 3.0 T MR field

Author:

Liu Shuwen1,Tegafaw Tirusew1ORCID,Yue Huan1,Ho Son Long1ORCID,Kim Soyeon2ORCID,Park Ji Ae2,Baek Ahrum3,Ahmad Mohammad Yaseen1,Yang So Hyeon3,Hwang Dong Wook3,Kim Seungho3,Ali Al Saidi Abdullah Khamis1ORCID,Zhao Dejun1,Liu Ying1,Nam Sung-Wook4ORCID,Chae Kwon Seok5,Chang Yongmin4,Lee Gang Ho1ORCID

Affiliation:

1. Department of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, South Korea

2. Division of RI-Convergence Research, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul 01817, South Korea

3. Department of Medical & Biological Engineering, Kyungpook National University, Taegu 41944, South Korea

4. Department of Molecular Medicine, School of Medicine, Kyungpook National University, Taegu 41944, South Korea

5. Department of Biology Education, Teachers’ College, Kyungpook National University, Taegu 41566, South Korea

Abstract

Paramagnetic ultrasmall Ho2O3 and Tm2O3 nanoparticles grafted with various hydrophilic and biocompatible ligands as a new class of efficient T2 MRI contrast agents were investigated in this study.

Funder

National Research Foundation

Ministry of Education, Science and Technology

Korea Institute of Radiological and Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

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