Click-based amplification: designed to facilitate various target labelling modes with ultralow background amplification-Reference-Cited by-同舟云学术

Click-based amplification: designed to facilitate various target labelling modes with ultralow background amplification

Published:2021 Issue:3 Volume:2 Page:906-916
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Bai Jinyi¹²³⁴⁵,Guo Fusheng¹²³⁴⁵,Li Mengyao⁶⁷⁸⁹¹⁰,Li Yulong¹¹¹²¹³¹⁴¹⁵,Lei Xiaoguang¹²³⁴⁵^ORCID

Affiliation:

1. Beijing National Laboratory for Molecular Sciences

2. State Key Laboratory of Natural and Biomimetic Drugs

3. Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education

4. Department of Chemical Biology

5. College of Chemistry and Molecular Engineering

6. State Key Laboratory of Membrane Biology

7. Peking University School of Life Sciences

8. Beijing

9. China

10. PKU-IDG/McGovern Institute for Brain Research

11. Peking-Tsinghua Center for Life Sciences

12. Academy for Advanced Interdisciplinary Studies

13. Peking University

14. Beijing 100871

15. People's Republic of China

Abstract

We describe a signal amplification method termed “Click-based amplification” that can be well integrated with various click-labelling modes, including chemical labelling, genetic incorporation and covalent inhibitor probe mediated target labelling.

Funder

National Natural Science Foundation of China

National Key Research & Development Plan

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CB/D1CB00002K

Reference30 articles.

1. Catalyzed reporter deposition, a novel method of signal amplification application to immunoassays

2. From The Cover: Triggered amplification by hybridization chain reaction

3. A hybridization-chain-reaction-based method for amplifying immunosignals

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5. The quantitative proteome of a human cell line

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