Versatile synthesis of oxime-containing acyclic nucleoside phosphonates – synthetic solutions and antiviral activity-Reference-Cited by-同舟云学术

Versatile synthesis of oxime-containing acyclic nucleoside phosphonates – synthetic solutions and antiviral activity

Published:2015 Issue:44 Volume:13 Page:10946-10956
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Solyev Pavel N.¹²³⁴,Jasko Maxim V.¹²³⁴,Kleymenova Alla A.¹²³⁴,Kukhanova Marina K.¹²³⁴,Kochetkov Sergey N.¹²³⁴

Affiliation:

1. Engelhardt Institute of Molecular Biology

2. Russian Academy of Sciences

3. 119991 Moscow

4. Russia

Abstract

New oxime-containing acyclic nucleoside phosphonates 9-{2-[(phosphonomethyl)oximino]ethyl}adenine (1), -guanine (2) and 9-{2-[(phosphonomethyl)oximino]propyl}adenine (3) with wide spectrum activity against different types of viruses were synthesized.

Funder

Russian Foundation for Basic Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01571E

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