Dietary astaxanthin-rich extract ameliorates atherosclerosis/retinopathy and restructures gut microbiome in apolipoprotein E-deficient mice fed on a high-fat diet

Author:

Liu Dong12ORCID,Ji Yanglin1,Cheng Qian3,Zhu Yamin3,Zhang Haibo3,Guo Yatu4,Cao Xiupeng5,Wang Hao1ORCID

Affiliation:

1. State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science & Technology, No. 29, 13th Avenue, Economic and Technological Development Area (TEDA), Tianjin 300457, China

2. Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Suzhou Medical College of Soochow University, Suzhou 215123, China

3. Angel Nutritech Company Limited, Yichang 443000, China

4. Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin 300384, China

5. The First People's Hospital of Neijiang, Neijiang 641099, China

Abstract

Astaxanthin against atherosclerosis/retinopathy are potentially mediated by increasing cholesterol efflux to intestine and at least in part by modulating bile acids and gut microbiota.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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