Resettable and enzyme-free molecular logic devices for the intelligent amplification detection of multiple miRNAs via catalyzed hairpin assembly-Reference-Cited by-同舟云学术

Resettable and enzyme-free molecular logic devices for the intelligent amplification detection of multiple miRNAs via catalyzed hairpin assembly

Published:2019 Issue:11 Volume:11 Page:5048-5057
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zhang Siqi¹²³⁴,Li Kai-Bin¹²³⁴,Shi Wei¹²³⁴,Zhang Jie¹²³⁴,Han De-Man¹²³⁴^ORCID,Xu Jing-Juan⁵⁶⁷⁸⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Taizhou University

3. Jiaojiang

4. China

5. State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences

6. School of Chemistry and Chemical Engineering

7. Nanjing University

8. Nanjing 210023

Abstract

In this work, we developed a magnetic bead/DNA system to construct a library of logic gates, enabling the sensing of multiplex target miRNAs. The CHA-based multiplex detection system can distinguish individual target miRNAs under a logic function control.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Taizhou Municipal Science and Technology Bureau

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NR/C8NR10103E

Reference37 articles.

1. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14