Protein denaturation caused by heat inactivation detrimentally affects biomolecular corona formation and cellular uptake-Reference-Cited by-同舟云学术

Protein denaturation caused by heat inactivation detrimentally affects biomolecular corona formation and cellular uptake

Published:2018 Issue:45 Volume:10 Page:21096-21105
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Simon Johanna¹²³⁴⁵^ORCID,Müller Julius¹²³⁴⁵,Ghazaryan Artur⁵⁶⁴,Morsbach Svenja⁵⁶⁴^ORCID,Mailänder Volker¹²³⁴⁵^ORCID,Landfester Katharina⁵⁶⁴^ORCID

Affiliation:

1. Dermatology Clinic

2. University Medical Center of the Johannes Gutenberg-University Mainz

3. 55131 Mainz

4. Germany

5. Max Planck Institute for Polymer Research

6. 55128 Mainz

Abstract

Adsorption of blood proteins to the surface of nanocarriers is known to be the critical factor influencing cellular interactions and eventually determining the successful application of nanocarriers as drug carriersin vivo.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NR/C8NR07424K

Reference62 articles.

1. Cancer nanomedicine: from targeted delivery to combination therapy

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3. Targeted and controlled anticancer drug delivery and release with magnetoelectric nanoparticles

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