Direct access to various C3-substituted sialyl glycal derivatives from 3-iodo-sialyl glycals-Reference-Cited by-同舟云学术

Direct access to various C3-substituted sialyl glycal derivatives from 3-iodo-sialyl glycals

Published:2021 Issue:46 Volume:19 Page:10169-10173
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Qingjiang¹,Guo Jiatong¹,Guo Zhongwu¹^ORCID

Affiliation:

1. Department of Chemistry, University of Florida, 214 Leigh Hall, Gainesville, Florida 32611, USA

Abstract

Sialyl glycal C3-aryl, alkyl, alkenyl, and alkynyl derivatives useful for sialylidase inhibitor discovery were efficiently synthesized by a new method based on the cross-coupling of 3-iodo-sialyl glycal with boronic acids, alkenes, and alkynes.

Funder

National Institute of General Medical Sciences

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01977E

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