The palladium-catalyzed direct C3-cyanation of indoles using acetonitrile as the cyanide source-Reference-Cited by-同舟云学术

The palladium-catalyzed direct C3-cyanation of indoles using acetonitrile as the cyanide source

Published:2020 Issue:31 Volume:18 Page:6108-6114
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liu Bifu¹²³⁴,Liu Min¹²³⁴⁵^ORCID,Li Qiang⁶⁷⁸⁴⁶^ORCID,Li Yuanhua¹²³⁴,Feng Kejun¹²³⁴,Zhou Yongbo⁶⁹¹⁰⁴^ORCID

Affiliation:

1. School of Chemistry and Materials Engineering

2. Huizhou University

3. Huizhou

4. China

5. Key Laboratory of Jiangxi Province for Persistent Pollutants Control and Resources Recycle

6. College of Chemistry and Chemical Engineering

7. Liaocheng University

8. Liaocheng

9. Hunan University

10. Changsha 410082

Abstract

The palladium-catalyzed C3-cyanation of indoles via direct C–H functionalization was achieved utilizing CH₃CN as the cyanide source through transition-metal-catalyzed C–CN bond cleavage.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00485E

Reference58 articles.

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2. Practical Methodologies for the Synthesis of Indoles

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4. Direct carboxamidation of indoles by palladium-catalyzed C–H activation and isocyanide insertion

5. Selective degradation of splicing factor CAPERα by anticancer sulfonamides

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