Significant anti-inflammatory aziridine-containing indole alkaloids from the Chinese medicinal plant <i>Alstonia scholaris</i>-Reference-Cited by-同舟云学术

Significant anti-inflammatory aziridine-containing indole alkaloids from the Chinese medicinal plant Alstonia scholaris

Published:2023 Issue:16 Volume:59 Page:2271-2274
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Hu Bin-Yuan¹,Zhao Yun-Li¹,Zhou Zhong-Shun¹,Zhu Yan-Yan¹,Luo Xiao-Dong¹²^ORCID

Affiliation:

1. Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, 650501, P. R. China

2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences Kunming, 650201, P. R. China

Abstract

Alstolactines D (1) and E (2), two unprecedented indole alkaloids with an aziridine scaffold, exhibited significant anti-inflammatory bioactivity.

Funder

Yunnan Provincial Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D2CC07029D

Reference33 articles.

1. Aziridines: epoxides’ ugly cousins?

2. Regioselectivity in the ring opening of non-activated aziridines

3. Aziridine alkaloids as potential therapeutic agents

4. Synthesis-Enabled Probing of Mitosene Structural Space Leads to Improved IC50over Mitomycin C

5. Cyclic Disulfide C(8) Iminoporfiromycin: Nucleophilic Activation of a Porfiromycin

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