A high-throughput multi-microfluidic crystal generator (MMicroCryGen) platform for facile screening of polymorphism and crystal morphology for pharmaceutical compounds-Reference-Cited by-同舟云学术

A high-throughput multi-microfluidic crystal generator (MMicroCryGen) platform for facile screening of polymorphism and crystal morphology for pharmaceutical compounds

Published:2018 Issue:15 Volume:18 Page:2235-2245
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Simone E.¹²³⁴⁵^ORCID,McVeigh J.⁵⁶⁷⁴,Reis N. M.⁵⁶⁷⁴⁵^ORCID,Nagy Z. K.⁵⁶⁷⁴⁸^ORCID

Affiliation:

1. School of Food Science and Nutrition

2. University of Leeds

3. Leeds

4. UK

5. Department of Chemical Engineering

6. Loughborough University

7. Loughborough

8. Davidson School of Chemical Engineering

Abstract

The MMicroCryGen allows single crystal generation and screening using 200 μL of solvent and without complex fluid handling (‘dipstick’ mode).

Funder

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2018/LC/C8LC00301G

Reference38 articles.

1. Polymorphism − A Perspective

2. J. Bernstein , Polymorphism in molecular crystals, First , Oxford Science Publication , 2002

3. H. G. Brittain , Polymorphism in pharmaceutical solids, Second , CRC Press Taylor a& Francis Group , 2009

4. A practical guide to pharmaceutical polymorph screening & selection

5. Vibrational Spectroscopic Studies of Cocrystals and Salts. 1. The Benzamide−Benzoic Acid System

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