Rational design of an immunoconjugate for selective knock-down of leukemia-specific E2A–PBX1 fusion gene expression in human Pre-B leukemia-Reference-Cited by-同舟云学术

Rational design of an immunoconjugate for selective knock-down of leukemia-specific E2A–PBX1 fusion gene expression in human Pre-B leukemia

Published:2012-09-18 Issue:1 Volume:5 Page:122-132
ISSN:1757-9708
Container-title:Integrative Biology
language:en
Short-container-title:

Author:

Uckun Fatih M.¹²³,Qazi Sanjive⁴,Dibirdik Ilker¹³,Myers Dorothea E.¹³

Affiliation:

1. Developmental Therapeutics Program, Children's Hospital Los Angeles, Children's Center for Cancer and Blood Diseases, Los Angeles, CA 90027, USA

2. Department of Pediatrics and Norris Comprehensive Cancer Center, Keck School of Medicine and Keck Medical Center of University of Southern California, Los Angeles, CA 90027, USA

3. Biotherapy Program, Parker Hughes Institute, St. Paul, MN 55455, USA

4. Department of Biology and Bioinformatics Program, Gustavus Adolphus College, St. Peter, MN 56082, USA

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Link

http://academic.oup.com/ib/article-pdf/5/1/122/27442188/c2ib20114c.pdf

Reference45 articles.

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3. The helix-loop-helix gene E2A is required for B cell formation;Zhuang;Cell,1994

4. Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia;Wiemels;Proc. Natl. Acad. Sci. U. S. A.,2002

5. Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): a Pediatric Oncology Group study;Crist;Blood,1990

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