Cytotoxic (salen)ruthenium(iii) anticancer complexes exhibit different modes of cell death directed by axial ligands-Reference-Cited by-同舟云学术

Cytotoxic (salen)ruthenium(iii) anticancer complexes exhibit different modes of cell death directed by axial ligands

Published:2017 Issue:10 Volume:8 Page:6865-6870
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Cai¹²³⁴⁵,Ip Kwok-Wa¹²³⁴,Man Wai-Lun¹²³⁴^ORCID,Song Dan⁶²³⁴,He Ming-Liang⁶²³⁴,Yiu Shek-Man¹²³⁴,Lau Tai-Chu¹²³⁴⁷^ORCID,Zhu Guangyu¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. City University of Hong Kong

3. Kowloon Tong

4. Hong Kong SAR

5. City University of Hong Kong Shenzhen Research Institute

6. Department of Biomedical Sciences

7. Institute of Molecular Functional Materials

Abstract

A cancer-cell selective bis(guanidine)-ruthenium(iii) complex induces apoptosis, whereas its amidine analogue effectively kills cancer cells through paraptosis pathways.

Funder

National Natural Science Foundation of China

City University of Hong Kong

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC02205K

Reference37 articles.

1. Modifications of DNA by platinum complexes

2. The resurgence of platinum-based cancer chemotherapy

3. Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes

4. Ruthenium complexes can target determinants of tumour malignancy

5. KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

Cited by 49 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Insights into the antineoplastic activity and mechanisms of action of coumarin-coordinated 8-hydroxyquinoline ruthenium(II/III) compounds;Journal of Inorganic Biochemistry;2024-10

2. Design, synthesis, and biological evaluation of novel halogenated chlorido[N,N′-bis(salicylidene)-1,2-bis(3-methoxyphenyl)ethylenediamine]iron(III) complexes as anticancer agents;JBIC Journal of Biological Inorganic Chemistry;2024-08-12

3. Synthesis of Optically Pure Cyclometalated Iridium(III) Complex‐Peptide Hybrids and Their Anticancer Activity;European Journal of Inorganic Chemistry;2024-05-31

4. Pt–S Bond-Enabled Temperature-Dependent Phosphorescence in S-Heteroaryl Tetradentate Pt(S^C^N^O) Complexes;Inorganic Chemistry;2024-05-02

5. In vitro and in vivo antitumor activities of Ru and Cu complexes with terpyridine derivatives as ligands;Journal of Inorganic Biochemistry;2023-09