Potential mechanism of action of Ixeris sonchifolia extract injection against cardiovascular diseases revealed by combination of HPLC-Q-TOF-MS, virtual screening and systems pharmacology approach

Author:

Xie Rongfang12345,Liu Zhenzhen12345,Lin Zuan12345,Shi Peiying67895ORCID,Chen Bing12345,Li Shaoguang12345,Li Guangwen102345,Huang Liying12345,Lin Xinhua12345,Yao Hong12345ORCID

Affiliation:

1. Department of Pharmaceutical Analysis

2. School of Pharmacy

3. Fujian Medical University

4. Fuzhou 350122

5. China

6. Department of Traditional Chinese Medicine Resource and Bee Products

7. Animal Science College

8. Fujian Agriculture and Forestry University

9. Fuzhou

10. Experimental Center of Chemistry

Abstract

Ixeris sonchifolia extract injection, a Chinese medicine preparation named as Kudiezi injection (KDZI) in China, has been widely used for the treatment of cardiovascular diseases (CVDs) in recent years.

Funder

Natural Science Foundation of Fujian Province

Program for New Century Excellent Talents in University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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