Systemic and characteristic metabolites in the serum of streptozotocin-induced diabetic rats at different stages as revealed by a1H-NMR based metabonomic approach-Reference-Cited by-同舟云学术

Systemic and characteristic metabolites in the serum of streptozotocin-induced diabetic rats at different stages as revealed by a1H-NMR based metabonomic approach

Published:2014 Issue:3 Volume:10 Page:686-693
ISSN:1742-206X
Container-title:Mol. BioSyst.
language:en
Short-container-title:Mol. BioSyst.

Author:

Diao Chengfeng¹²³⁴⁵,Zhao Liangcai⁵⁶³⁷,Guan Mimi⁵⁶³⁷,Zheng Yongquan⁵⁶³⁷,Chen Minjiang⁵⁶³⁷,Yang Yunjun¹²³⁴,Lin Li⁵⁶³⁷,Chen Weijian¹²³⁴,Gao Hongchang¹²³⁴⁵

Affiliation:

1. Department of Radiology

2. the first Affiliated Hospital

3. Wenzhou Medical University

4. Wenzhou 325000, PR China

5. Institute of Metabonomics & Pharmaceutical NMR

6. School of Pharmacy

7. Wenzhou 325035, PR China

Abstract

A schematic diagram of the disturbed metabolic pathways showing that glycolysis, the TCA cycle, glucogeogenesis andetc. are involved in the evolution of diabetes.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MB/C3MB70609E

Reference32 articles.

1. Global Prevalence of Diabetes

2. Type-I Diabetes: A Chronic Autoimmune Disease of Human, Mouse, and Rat

3. Metabonomics and diabetes mellitus

4. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

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