Regioselective synthesis and biological evaluation ofN-substituted 2-aminoquinazolin-4-ones-Reference-Cited by-同舟云学术

Regioselective synthesis and biological evaluation ofN-substituted 2-aminoquinazolin-4-ones

Published:2018 Issue:24 Volume:16 Page:4482-4494
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liao Zhen-Yuan¹²³⁴,Yeh Wen-Hsiung¹²³⁴,Liao Pen-Yuan¹²³⁴,Liu Yu-Ting¹²³⁴,Chen Ying-Cheng¹²³⁴,Chen Yi-Hung¹²³⁴,Hsieh Tsung-Han¹²³⁴,Lin Chia-Chi¹²³⁴,Lu Ming-Hsuan¹²³⁴,Chen Yi-Song⁵⁶⁷⁸⁴,Hsu Ming-Chih⁵⁶⁷⁸⁴,Li Tsai-Kun⁵⁶⁷⁸⁴,Chien Tun-Cheng¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. National Taiwan Normal University

3. Taipei 116

4. Taiwan

5. Department and Graduate Institute of Microbiology

6. College of Medicine

7. National Taiwan University

8. Taipei 100

Abstract

The reaction of methyl anthranilates withN-arylcyanamides can selectively form two different regioisomericN-substituted 2-aminoquinazolin-4-one derivatives.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00624E

Reference91 articles.

1. Bifunctional Hydrogen-Bond Donors That Bear a Quinazoline or Benzothiadiazine Skeleton for Asymmetric Organocatalysis

2. Tricyclic Quinazoline Alkaloids: Isolation, Synthesis, Chemical Modification, and Biological Activity

3. Rapid Syntheses of Biologically Active Quinazolinone Natural Products Using Microwave Technology