Organocatalytic C3-functionalization of indolizines: synthesis of biologically important indolizine derivatives-Reference-Cited by-同舟云学术

Organocatalytic C3-functionalization of indolizines: synthesis of biologically important indolizine derivatives

Published:2020 Issue:29 Volume:18 Page:5688-5696
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Yi-Zhu¹²³⁴,Sheng Feng-Tao¹²³⁴,Zhu Zuoquan⁵⁶⁷⁴,Li Zhi-Ming¹²³⁴,Zhang Shu⁵⁶⁷⁴,Tan Wei¹²³⁴,Shi Feng¹²³⁴^ORCID

Affiliation:

1. School of Chemistry and Materials Science

2. Jiangsu Normal University

3. Xuzhou

4. China

5. Department of Radiation Oncology and the Department of Radiotherapy

6. the First Affiliated Hospital of Nanjing Medical University

7. Nanjing

Abstract

A Brønsted acid-catalyzed C3-alkylation of indolizines has been established with different electrophiles (E), which synthesized a series of C3-functionalized indolizines in overall good yields (up to 89%).

Funder

National Natural Science Foundation of China

Jiangsu Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01230K

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