Coupling of RAFT polymerization and chemoselective post-modifications of elastin-like polypeptides for the synthesis of gene delivery hybrid vectors-Reference-Cited by-同舟云学术

Coupling of RAFT polymerization and chemoselective post-modifications of elastin-like polypeptides for the synthesis of gene delivery hybrid vectors

Published:2021 Issue:2 Volume:12 Page:226-241
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Bravo-Anaya Lourdes Mónica¹²³⁴⁵^ORCID,Rosselgong Julien¹²³⁴⁵,Fernández-Solís Karla Gricelda¹²³⁴⁵,Xiao Ye¹²³⁴⁵,Vax Amélie¹²³⁴⁵,Ibarboure Emmanuel¹²³⁴⁵,Ruban Anna¹²³⁴⁵,Lebleu Coralie¹²³⁴⁵,Joucla Gilles¹²³⁴⁵,Garbay Bertrand¹²³⁴⁵,Garanger Elisabeth¹²³⁴⁵,Lecommandoux Sébastien¹²³⁴⁵

Affiliation:

1. University of Bordeaux

2. CNRS

3. Bordeaux INP

4. Pessac

5. France

Abstract

Hybrid cationic ELPs for nucleic acids transport and delivery were synthetized through the coupling of RAFT polymerization and biorthogonal chemistry of ELPs, introducing a specific number of positive charges to the ELP backbone.

Funder

Consejo Nacional de Ciencia y Tecnología

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/PY/D0PY01293A

Reference107 articles.

1. Smart hybrid materials by conjugation of responsive polymers to biomacromolecules

2. Synthetic polymers for biopharmaceutical delivery