Cytotoxic peptide conjugates of dinuclear arene ruthenium trithiolato complexes-Reference-Cited by-同舟云学术

Cytotoxic peptide conjugates of dinuclear arene ruthenium trithiolato complexes

Published:2015 Issue:2 Volume:6 Page:347-350
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Giannini Federico¹²³⁴,Bartoloni Marco¹²³⁴,Paul Lydia E. H.¹²³⁴,Süss-Fink Georg⁵⁶⁷⁴,Reymond Jean-Louis¹²³⁴,Furrer Julien¹²³⁴

Affiliation:

1. Departement für Chemie und Biochemie

2. Universität Bern

3. CH-3012 Bern

4. Switzerland

5. Institut de Chimie

6. Université de Neuchâtel

7. CH-2000 Neuchâtel

Abstract

Novel dinuclear arene ruthenium trithiolato complexes containing a water-soluble peptide moiety in one of the three thiolato bridges were designed and evaluated against A2780 human ovarian cancer cells and against their cisplatin-resistant mutant A2780cisR.

Funder

Swiss National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C4MD00433G

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