Surface-engineered mesoporous silica particles with luminescent, cytocompatible and targeting properties for cancer cell imaging

Author:

Tagaya Motohiro1234ORCID,Abe Shigeaki5674,Motozuka Satoshi89104,Shiba Kota111213144,Takemura Taro1513144,Hayashi Ikuo1617184,Sakaguchi Yoshimitsu1617184

Affiliation:

1. Department of Materials Science and Technology

2. Nagaoka University of Technology

3. Nagaoka

4. Japan

5. Graduate School of Dental Medicine

6. Hokkaido University

7. Sapporo 060-8586

8. Department of Mechanical Engineering

9. Gifu National College of Technology

10. Motosu

11. World Premier International Research Center Initiative (WPI)

12. International Center for Materials Nanoarchitectonics (MANA)

13. National Institute for Materials Science (NIMS)

14. Tsukuba

15. Nanotechnology Innovation Station

16. Graduate School of Engineering

17. Nagoya University

18. Nagoya 464-8603

Abstract

Mechanochemically-treated europium(iii)-doped mesoporous silica particles were prepared, and a targeting ligand for cancer cells was immobilized. The surface-engineered particles exhibited the clear imaging along with all the cellular shapes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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