35Cl solid-state NMR of HCl salts of active pharmaceutical ingredients: structural prediction, spectral fingerprinting and polymorph recognition
Author:
Affiliation:
1. Department of Chemistry and Biochemistry
2. University of Windsor
3. Windsor, Canada N9B 3P4
4. National High Magnetic Field Laboratory
5. Tallahassee, USA
Abstract
A series of HCl salts of active pharmaceutical ingredients (APIs) have been characterized via35Cl solid-state NMR (SSNMR) spectroscopy and first-principles plane-wave DFT calculations of 35Cl NMR interaction tensors.
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/CE/C4CE00544A
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