Improvement of high-glucose and insulin resistance of chromium malate in 3T3-L1 adipocytes by glucose uptake and insulin sensitivity signaling pathways and its mechanism-Reference-Cited by-同舟云学术

Improvement of high-glucose and insulin resistance of chromium malate in 3T3-L1 adipocytes by glucose uptake and insulin sensitivity signaling pathways and its mechanism

Published:2019 Issue:1 Volume:9 Page:114-127
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Feng Weiwei¹²³⁴⁵,Liu Yongchao¹²³⁴⁵,Fei Fan¹²³⁴⁵,Chen Yao¹²³⁴⁵,Ding Yangyang¹²³⁴⁵,Yan Mengjiao¹²³⁴⁵,Feng Yun⁶³⁴⁵,Zhao Ting⁷³⁴⁵,Mao Guanghua¹²³⁴⁵,Yang Liuqing⁷³⁴⁵^ORCID,Wu Xiangyang¹²³⁴⁵

Affiliation:

1. Institute of Environmental Health and Ecological Security

2. School of the Environment and Safety Engineering

3. Jiangsu University

4. 212013 Zhenjiang

5. China

6. School of Medical Science and Laboratory Medicine

7. School of Chemistry and Chemical Engineering

Abstract

Chromium malate could increase the related protein and mRNA levels in 3T3-L1 adipocytes with insulin resistant. Pretreatment with the inhibitor completely/partially inhibited the GLUT-4 and Irs-1 proteins and mRNA expression compared to model group.

Funder

National Natural Science Foundation of China

Jiangsu University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C8RA07470D

Reference40 articles.

1. Clinical Pharmacokinetics and Pharmacodynamics of Antihyperglycemic Medications in Children and Adolescents with Type 2 Diabetes Mellitus

2. World Health Organization (WHO) , http://apps.who.int/iris/bitstream/10665/204871/1/9789241565257_eng.pdf , 2016 , accessed November 2016