A formal vinylic substitution reaction for the synthesis of α,β-unsaturated enol esters and their anticancer potential-Reference-Cited by-同舟云学术

A formal vinylic substitution reaction for the synthesis of α,β-unsaturated enol esters and their anticancer potential

Published:2024 Issue:16 Volume:22 Page:3273-3278
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Swami Bhawna¹,Kumari Neetu²,Maruthi Mulaka²,Kunjunny Neethu K.³,Menon Rajeev S.³^ORCID

Affiliation:

1. Department of Chemistry, Central University of Haryana, Mahendergarh, Haryana 123 031, India

2. Department of Biochemistry, Central University of Haryana, Mahendergarh, Haryana 123 031, India

3. Department of Chemistry, University of Calicut, Malappuram, Kerala 673 635, India

Abstract

Cesium carbonate promoted a ‘formal vinylic substitution’ of the bromine in 2-bromoallyl sulfones by α,β-unsaturated acids. The arylsulfonyl group-bearing enol esters thus produced displayed promising levels of anticancer activity.

Funder

University Grants Commission

Science and Engineering Research Board

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00401A

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