<i>Lactobacillus plantarum</i> AR495 improves colonic transport hyperactivity in irritable bowel syndrome through tryptophan metabolism-Reference-Cited by-同舟云学术

Lactobacillus plantarum AR495 improves colonic transport hyperactivity in irritable bowel syndrome through tryptophan metabolism

Published:2024 Issue:14 Volume:15 Page:7416-7429
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhang Hongyun¹²,Xia Yongjun¹^ORCID,Wang Guangqiang¹,Xiong Zhiqiang¹,Wei Guoliang²,Liao Zhuan³,Qian Yangyan³,Cai Zongwei⁴^ORCID,Ai Lianzhong¹^ORCID

Affiliation:

1. Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China

2. Business school, University of Shanghai for Science and Technology, Shanghai, 200093, China

3. Department of Gastroenterol, Digestive Endoscopy Center, Changhai Hospital, Shanghai, 200433, China

4. State Key Laboratory of Environmental & Biological Analysis, Hong Kong Baptist University, Hong Kong Special Administrative region of China, China

Abstract

L. plantarum AR495 could restore the normal levels of 5-HT by inhibiting the abnormal proliferation of enterochromaffin cells and the excessive activation of TPH1 to inhibit the intestinal peristalsis in IBS.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO01087F

Reference56 articles.

1. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV

2. Effectiveness of the Chinese Herbal Formula TongXieYaoFang for Irritable Bowel Syndrome: A Systematic Review

3. Long-term efficacy and safety of ramosetron in the treatment of diarrhea-predominant irritable bowel syndrome

4. Intestinal Serotonin Release, Sensory Neuron Activation, and Abdominal Pain in Irritable Bowel Syndrome