Fluorine in fragrances: exploring the difluoromethylene (CF2) group as a conformational constraint in macrocyclic musk lactones-Reference-Cited by-同舟云学术

Fluorine in fragrances: exploring the difluoromethylene (CF2) group as a conformational constraint in macrocyclic musk lactones

Published:2016 Issue:1 Volume:14 Page:211-219
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Corr Michael J.¹²³⁴,Cormanich Rodrigo A.⁵⁶⁷⁸,von Hahmann Cortney N.¹²³⁴,Bühl Michael¹²³⁴,Cordes David B.¹²³⁴,Slawin Alexandra M. Z.¹²³⁴,O'Hagan David¹²³⁴

Affiliation:

1. School of Chemistry

2. University of St Andrews

3. St Andrews

4. UK

5. Chemistry Institute

6. University of Campinas

7. Campinas

8. Brazil

Abstract

The synthesis of a series of selectively fluorinated musk lactones is reported with CF₂ groups at various locations to bias conformation the ring.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02023A

Reference35 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Oxidative Aliphatic C-H Fluorination with Fluoride Ion Catalyzed by a Manganese Porphyrin

3. Fluorine in medicinal chemistry

4. Understanding organofluorine chemistry. An introduction to the C–F bond

5. Trifluoromethyl ethers – synthesis and properties of an unusual substituent

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