Deletion of the side chain assembly reveals diverse post-PKS modifications in the biosynthesis of ansatrienins-Reference-Cited by-同舟云学术

Deletion of the side chain assembly reveals diverse post-PKS modifications in the biosynthesis of ansatrienins

Published:2016 Issue:91 Volume:6 Page:88571-88579
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Xiaomei¹²³⁴⁵,Zhu Jing⁶⁷³⁴⁵,Shi Guoyin⁶⁷³⁴⁵,Sun Mingwei¹²³⁴⁵,Guo Zhixing¹²³⁴⁵,Wang Haoxin⁶⁷³⁴⁵,Lu Chunhua¹²³⁴⁵,Shen Yuemao¹²³⁴⁵

Affiliation:

1. Key Laboratory of Chemical Biology (Ministry of Education)

2. School of Pharmaceutical Sciences

3. Shandong University

4. Jinan

5. P. R. China

6. State Key Laboratory of Microbial Technology

7. School of Life Sciences

Abstract

Seven new ansatrienols were extracted from Streptomyces sp., and 3 showed anti-T3SS activity, demonstrating diverse post-PKS modifications during ansatrienin biosynthesis.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA19036G

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