Cell response and bone ingrowth to 3D printed Ti6Al4V scaffolds with Mg-incorporating sol–gel Ta2O5 coating

Author:

Zhang Bo1,Feng Jun1,Chen Shuo1,Liao Ruohan1,Zhang Chengdong12,Luo Xuwei1,Yang Zelong1,Xiao Dongqin1ORCID,He Kui3,Duan Ke3

Affiliation:

1. Research Institute of Tissue Engineering and Stem Cells, Department of Orthopaedics, Nanchong Central Hospital, The Second Clinical College of North Sichuan Medical College, Nanchong, Sichuan 637000, China

2. Key Laboratory of Advanced Technologies of Materials (MOE), School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031, China

3. Sichuan Provincial Laboratory of Orthopaedic Engineering, Department of Orthopaedics, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China

Abstract

A Mg-incorporating Ta coating was deposited on a 3D-printed Ti6Al4V scaffold using a sol–gel method. The coating enhanced osteogenic differentiation of BMSCs and bone ingrowth in vivo.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Sichuan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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