Highly sensitive detection of nucleic acids using a cascade amplification strategy based on exonuclease III-assisted target recycling and conjugated polyelectrolytes-Reference-Cited by-同舟云学术

Highly sensitive detection of nucleic acids using a cascade amplification strategy based on exonuclease III-assisted target recycling and conjugated polyelectrolytes

Published:2018 Issue:18 Volume:143 Page:4267-4272
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Bao Biqing¹²³⁴⁵,Pan Yanrui¹²³⁴⁵,Gu Bingbing¹²³⁴⁵,Chen Jia¹²³⁴⁵,Xu Yu¹²³⁴⁵,Su Peng¹²³⁴⁵,Liu Yunfei¹²³⁴⁵,Tong Li¹²³⁴⁵,Wang Lianhui¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory for Organic Electronics and Information Displays (KLOEID) & Jiangsu Key Laboratory for Biosensors

2. Institute of Advanced Materials (IAM)

3. Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM)

4. Nanjing University of Posts and Telecommunications (NUPT)

5. Nanjing 210023

Abstract

A ratiometric and cascade amplification strategy that combines the signal amplification and effecitive FRET property of CPEs with the Exo III-assisted target recycling method has been developed for DNA detection.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/AN/C8AN01024B

Reference34 articles.

1. Novel biosensing methodologies for improving the detection of single nucleotide polymorphism

2. An electrochemical DNA sensor without electrode pre-modification