ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate dynamics in living cells-Reference-Cited by-同舟云学术

ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate dynamics in living cells

Published:2024 Issue:6 Volume:5 Page:544-555
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Ajiki Moeka¹,Yoshikawa Masaru²,Miyazaki Tomoki¹,Kawasaki Asami³^ORCID,Aoki Kazuhiro⁴⁵⁶^ORCID,Nakatsu Fubito³^ORCID,Tsukiji Shinya¹²^ORCID

Affiliation:

1. Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan

2. Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan

3. Department of Neurochemistry and Molecular Cell Biology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi, Chuo-ku, Niigata 951-8510, Japan

4. Quantitative Biology Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan

5. Division of Quantitative Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan

6. Department of Basic Biology, Faculty of Life Science, SOKENDAI (The Graduate University for Advanced Studies), 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan

Abstract

New fluorescent reporters based on the ORP9 PH domain visualize phosphatidylinositol 4-phosphate (PI4P) dynamics at multiple cellular locations with high specificity and contrast in live-cell imaging.

Funder

Japan Agency for Medical Research and Development

National Institutes of Natural Sciences

Takeda Science Foundation

Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CB/D3CB00232B

Reference76 articles.

1. Phosphoinositides in cell regulation and membrane dynamics

2. Phosphoinositides as membrane organizers

3. Mammalian phosphoinositide kinases and phosphatases

4. The chemistry and biology of phosphatidylinositol 4-phosphate at the plasma membrane

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion;Biochemical and Biophysical Research Communications;2024-07