Uridine attenuates obesity, ameliorates hepatic lipid accumulation and modifies the gut microbiota composition in mice fed with a high-fat diet

Author:

Liu Yilin12345,Xie Chunyan67859,Zhai Zhenya101112135,Deng Ze-yuan12345,De Jonge Hugo R.9141516,Wu Xin12345ORCID,Ruan Zheng12345ORCID

Affiliation:

1. School of Food Science and Technology

2. State Laboratory of Food Science and Technology

3. Nanchang University

4. Nanchang

5. China

6. Tianjin Institute of Industrial Biotechnology

7. Chinese Academy of Sciences

8. Tianjin

9. Department of Gastroenterology and Hepatology

10. Key Laboratory of Agro-ecological Processes in Subtropical Region

11. Institute of Subtropical Agriculture

12. the Chinese Academy of Sciences

13. Changsha 410125

14. Erasmus MC University Medical Center

15. Rotterdam

16. Netherlands

Abstract

This study aimed to investigate the effect of uridine on obesity, fat accumulation in liver, and gut microbiota composition in high-fat diet-fed mice.

Funder

National Key Research and Development Program of China

Science and Technology Program of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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