Hydrogel microstructure live-cell array for multiplexed analyses of cancer stem cells, tumor heterogeneity and differential drug response at single-element resolution-Reference-Cited by-同舟云学术

Hydrogel microstructure live-cell array for multiplexed analyses of cancer stem cells, tumor heterogeneity and differential drug response at single-element resolution

Published:2016 Issue:6 Volume:16 Page:1047-1062
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Afrimzon E.¹²³⁴⁵,Botchkina G.⁶⁷⁸⁹¹⁰,Zurgil N.¹²³⁴⁵,Shafran Y.¹²³⁴⁵,Sobolev M.¹²³⁴⁵,Moshkov S.¹²³⁴⁵,Ravid-Hermesh O.¹²³⁴⁵,Ojima I.⁹¹⁰⁷⁸,Deutsch M.¹²³⁴⁵

Affiliation:

1. Physics Department

2. The Biophysical Interdisciplinary Schottenstein Center for the Research and Technology of the Cellome

3. Bar Ilan University

4. Ramat Gan

5. Israel

6. Department of Pathology

7. Stony Brook University

8. USA

9. Department of Chemistry

10. Institute of Chemical Biology & Drug Discovery

Abstract

High optical quality hydrogel array of nanoliter-volume micro-chambers for concomitant generation and multiplex analyses of numerous cancer stem cell spheroids.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/LC/C6LC00014B

Reference49 articles.

1. Cancer statistics, 2014

2. Stem cells, cancer, and cancer stem cells

3. Cancer Stem Cells: Current Status and Evolving Complexities

4. Cancer stem cells

5. Stem cell gene expression programs influence clinical outcome in human leukemia

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