Preparation and in vitro release kinetics of nitrendipine-loaded PLLA–PEG–PLLA microparticles by supercritical solution impregnation process
Author:
Affiliation:
1. College of Environmental and Chemical Engineering
2. Dalian University
3. Dalian
4. China
5. Chemical and Environmental Protection Engineering Technology Research Center of Liaoning Province
Abstract
In this work, drug-loaded polymer microparticles were prepared by a supercritical solution impregnation (SSI) process with nitrendipine as the model drug and PLLA–PEG–PLLA as the drug carrier.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA01068H
Reference38 articles.
1. Solubility of Felodipine and Nitrendipine in Liquid and Supercritical Carbon Dioxide by Cloud Point and UV Spectroscopy
2. Early stage release control of an anticancer drug by drug-polymer miscibility in a hydrophobic fiber-based drug delivery system
3. Production of submicron particles of the antioxidants of mango leaves/PVP by supercritical antisolvent extraction process
4. Production of biodegradable porous scaffolds impregnated with indomethacin in supercritical CO2
5. Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation
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